
Hands-on-Training
on
Bioinformatics
CytoGene offers training in Bioinformatics. Student can avail Hands-on-training of basic techniques at a nominal charges. The duration of the programs offered for 30 days has techniques of basic bioinformatic tools, Computational approach in Biological System and In-silico Drug Designing.
TRAINING INCLUDES
1. INTRODUCTION AND ANALYSIS OF DATABASE
This includes a thorough summarisation of fundamentals of tools required during training. This helps the candidate to gain basic knowledge.
3. DRY LAB WORK AND PERFORMING EXPERIMENTS
Students has to perform one by one all the listed experiments in any chooses modules, supervisor will instruct throughout training. The dry lab work has to be performed by students only on individual basis. Supervisor will not perform any experiments on behalf of candidate.
5. REVIEW OF COMPLETE WORK AND Q&A SESSION
A review of the complete work will be done by supervisor to ensure all the work done and findings are grasped by the candidates. There will be a question and answer session also to clear all the doubts and queries (if any).
2. DISCUSSION ON TOOLS AND PRACTICES
Before proceeding for any work the adaptation of basic practices is needed to ensure better handling of techniques and softwares.
4. DAILY RECORD OF WORK DONE IN LABORATORY MANUAL
All the results obtained during the work must be managed in very organised form with complete analysis. A manual will be provided by CytoGene at the beginning of training itself. The daily output of experiments have to be filled in this manual.
6. REPORT PREPARATION AND CERTIFICATE DISTRIBUTION
A compilation of entire work in the form of report has to be prepared by every student. All the results and finding has to be added in it along with the analysis (If any) by the students under constant guidance of supervisor
ALL TRAINING MODULES
MODULES FOR 7 DAYS

FUNDAMENTALS OF BIOINFORMATICS
-
Introduction to Bioinformatics (Basic & Application)
-
Introduction to NCBI & Study of various file formats
-
Alignment of sequences using BLAST
-
Primer designing for a given sequence
-
Gen sequence retrieval from nucleotide databases
-
Protein sequence retrieval from protein databases
-
Visualization of 3-D structure of proteins using various tools
-
Pairwise alignment using EMBOSS
-
IMultiple Sequence Alignment using various tools and Evolutionary relationship by Phylogenetic Analysis
Duration: 7 Days
Fee: 3500/- (Reg. fee 500 + Training Fee 3000)

COMPUTATIONAL APPROACH
FOR DRUG DESIGNING
-
Selection of target protein / gene
-
Literature study of selected gene/protein
-
Retrieval of target protein using UniProt
-
Subcellular localization prediction
-
Position of protein pathways analysis
-
Protein functional family classification
-
Secondary structure prediction
-
Homology Modelling
-
Docking of ligand with protein
Duration: 7 Days
Fee: 4000/- (Reg. fee 500 + Training Fee 3500)

DRUG DESIGNING AND MOLECULAR DYNOMICS SIMULATIONS
-
Protein retrieval and Active site prediction (RCSB - PDB, Discovery studio, CAST)
-
Selection of ligand and Dataset preparation (PubChem, ChemSpider, Open Babel)
-
Drug likeliness of compound and Screening of ligands on basis of Lipinski rule of 5
-
Ligand property prediction and screening (DriLiTo, ADMET-SAR, Swiss-ADME)
-
Homology modelling for structure of unknown proteins
-
Docking in Autodock Vina
-
Poses analysis using PyMol
-
Molecular Dynamics Simulation using GROMACS
-
Analysis of the plots of simulation
Duration: 7 Days
Fee: 5000/- (Reg. fee 500 + Training Fee 4500)
MODULES FOR 15 DAYS

BASIC BIOINFORMATICS AND
IN-SILICO DRUG DESIGNING
Basic Bioinformatics
-
ntroduction to Bioinformatics (Basic & Application)
-
Introduction to NCBI & Study of various file formats
-
Alignment of sequences using BLAST
-
Primer designing for a given sequence
-
Gen sequence retrieval from nucleotide databases
-
Protein sequence retrieval from protein databases
-
Visualization of 3-D structure of proteins using various tools
-
Pairwise alignment using EMBOSS
-
IMultiple Sequence Alignment using various tools and Evolutionary relationship by Phylogenetic Analysis
In-Silico Drug Designing
-
Selection of target protein / gene
-
Literature study of selected gene/protein
-
Retrieval of target protein using UniProt
-
Subcellular localization prediction
-
Position of protein pathways analysis
-
Protein functional family classification
-
Secondary structure prediction
-
Homology Modelling
-
Docking of ligand with protein
Duration: 15 Days
Fee: 5500/- (Reg. fee 500 + Training Fee 5000)

IN-SILICO DRUG DESIGNIN & MOLECULAR DYNOMICS SIMULATIONS
In-Silico Drug Designing
-
Selection of target protein / gene
-
Literature study of selected gene/protein
-
Retrieval of target protein using UniProt
-
Subcellular localization prediction
-
Position of protein pathways analysis
-
Protein functional family classification
-
Secondary structure prediction
-
Homology Modelling
-
Docking of ligand with protein
Molecular Dynomics Simulations
-
Protein retrieval and Active site prediction (RCSB - PDB, Discovery studio, CAST)
-
Selection of ligand and Dataset preparation (PubChem, ChemSpider, Open Babel)
-
Drug likeliness of compound and Screening of ligands on basis of Lipinski rule of 5
-
Ligand property prediction and screening (DriLiTo, ADMET-SAR, Swiss-ADME)
-
Homology modelling for structure of unknown proteins
-
Docking in Autodock Vina
-
Poses analysis using PyMol
-
Molecular Dynamics Simulation using GROMACS
-
Analysis of the plots of simulation
Duration: 15 Days
Fee: 6500/- (Reg. fee 500 + Training Fee 6000)
MODULE FOR 30 DAYS

FUNDAMENTAL OF BIOINFORMATICS
Basic Bioinformatics
-
Introduction to Bioinformatics & NCBI.
-
Study of various file formats.
-
Sequence retrieval from databases.
-
Alignment of sequences using BLAST.
-
Primer designing for a given sequence.
Comparative tools
-
Pairwise alignment using EMBOSS.
-
Multiple Sequence Alignment using various tools.
-
Phylogeny and Cladogram Analysis.
-
Complete genome comparison.
-
Analysis of percentage divergence between species.
-
Phylogenetic tree construction using various software’s
Prediction tools
-
Gene prediction tools.
-
Secondary structure prediction tool.
-
Ligand property prediction tool.
-
Toxicity and ADME properties prediction tool.
-
ORF finding tool.
-
Prediction of potential cleavage sites by ExPasy web tool.
Drug Designing approach
-
Active site prediction of target protein.
-
Retrieval of small Molecules from zinc Database/Pubchem
-
Drug linkliness of compound
-
Screening of ligands on basis of Lipinski rule of 5
-
Inter conversion of various file Conversion using software
-
Homology modeling for structure of unknown proteins
Docking of Protein and ligand
-
Protein preparation
-
Docking in Autodock Vina
-
Poses analysis using PyMol
-
Interaction of Protein-ligand residues in the active site
Duration: 30 Days
Fee: 8000/- (Reg. fee 500 + Training Fee 7500)

APPLICATION OF BIOINFORMATICS
Comparative tools
-
Pairwise alignment using EMBOSS.
-
Multiple Sequence Alignment using various tools.
-
Phylogeny and Cladogram Analysis.
-
Complete genome comparison.
-
Analysis of percentage divergence between species.
-
Phylogenetic tree construction using various software’s
Prediction tools
-
Gene prediction tools.
-
Secondary structure prediction tool.
-
Ligand property prediction tool.
-
Toxicity and ADME properties prediction tool.
-
ORF finding tool.
-
Prediction of potential cleavage sites by ExPasy web tool.
Drug Designing approach
-
Active site prediction of target protein.
-
Retrieval of small Molecules from zinc Database/Pubchem
-
Drug linkliness of compound
-
Screening of ligands on basis of Lipinski rule of 5
-
Inter conversion of various file Conversion using software
-
Homology modeling for structure of unknown proteins
-
Protein preparation
-
Docking in Autodock Vina
-
Poses analysis using PyMol
-
Interaction of Protein-ligand residues in the active site
Molecular Dynomics Simulations
-
Protein retrieval and Active site prediction (RCSB - PDB, Discovery studio, CAST)
-
Selection of ligand and Dataset preparation (PubChem, ChemSpider, Open Babel)
-
Drug likeliness of compound and Screening of ligands on basis of Lipinski rule of 5
-
Ligand property prediction and screening (DriLiTo, ADMET-SAR, Swiss-ADME)
-
Homology modelling for structure of unknown proteins
-
Docking in Autodock Vina
-
Poses analysis using PyMol
-
Molecular Dynamics Simulation using GROMACS
-
Analysis of the plots of simulation
Duration: 30 Days
Fee: 9000/- (Reg. fee 500 + Training Fee 8500)
COMPULSORY REQUIREMENT
-
Laptop is a must for this training
-
Link for Software will either be shared with you or you will have to download the software during training, We will let you know that in advance
-
A Lab coat

BATCHES IN 2023
Mar 15, April 01 & 17, May 01 & 15, June 01, 12, 19 & 26, July 01, 10 & 20
Register in any Batch
Till 31 March 2023 and get 10% OFF on training fee
or
Till 30 April 2023 and get 5% OFF on training fee

HOW TO REGISTER
Online Registration:
Click the blow given button to register online. Fill the form and submit. Pay registration fee Rs. 500/- by any given Mode. Confirmation letter will be generated and sent by email. Training fee can be paid after receiving of confirmation letter till the date of Joining.
Offline Registration:
Download MS Word format of Registration form.
Send the duly filled registration form and screenshot of payment by Email to training@cytogene.in or
Whatsapp to 77-0309-2222
Click to download registration form
CONTACT PERSON
Er. Sujeet Kumar Singh
Director
CytoGene Research & Development
Lucknow - 226021
+91-77-0309-2222 , +91-77-0309-3333
Enhance Your Bioinformatics Skills with Top-notch Training at CytoGene Research & Development Lucknow
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