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3 Month Online Project

on

"In-silico Drug Designing"

02 Jan – 01 April 2022 (6pm to 8pm, Mon – Fri)

30 Seats (First Come First Serve Basis)

PROJECT  INCLUDES

1. LITERATURE STUDY ON THE SELECTED TOPIC

This includes a thorough background study related to the required material by the research. This helps the candidate to gain basic knowledge on the topic.

3. TARGET SELECTION & PRACTICAL

Candidate has to select the targets from the data base as mentioned in their synopsis. This is the major step of the program. Candidate has to complete his/her entire practical work under the guidance of the faculty. No work will be done by the faculty, candidate has to perform the entire work by themselves.

5. REVIEW OF COMPLETE WORK

A review of the complete work followed by the viva voice is done for every student individually.

2. SYNOPSIS PRESENTATION

A layout of the entire work in the form of synopsis is prepared by the candidate under the guidance of the faculty. Synopsis is then presented by the candidate in the form of presentation to the guide and other faculty members. After correction candidate can move to next step.

4. DATA MANAGEMENT AND RESULT ANALYSIS

All the results obtained during the work must be managed in very organised form and complete its analysis.

6. REPORT PREPARATION

A compilation of entire work in the form of thesis is prepared by every student. All the steps will be performed  by the students under constant guidance of faculty

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TECHNIQUES TO BE USED EXTENSIVELY...

  1. Protein retrieval and Active site prediction (RCSB - PDB, Discovery studio, CASTp)

  2. Selection of ligand and Dataset preparation   (PubChem, ChemSpider, Open Babel)

  3. Drug likeliness of compound and Screening of  ligands on basis of Lipinski rule of 5

  4. Ligand property prediction and screening   (DriLiTo, ADMET-SAR, Swiss-ADME)

  5. Homology modelling for structure of   unknown proteins

  6. Protein and Ligand Preparation on ADT

  7. Docking in Autodock Vina

  8. Docking in PyRx

  9. Interaction of Protein-ligand residues in   the active site using LigPlot

  10. Poses analysis using PyMol

  11. Molecular Dynamics Simulation using GROMACS

  12. Analysis of the plots of simulations

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COMPULSORY REQUIREMENT

 

  1. A computer with Basic configuration

  2. An uninterrupted Internet Connection

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TRAINERS

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Dr. Madhulika Singh

Area of Specialisation: Molecular Biology & Bioinformatics

 

Research Experience: 8+ years

Trainees Undergone: 2500+

PUBLICATION

In future participants can publish the data collected during the project work.

 

As each member will work separately, no data will be shared in between and it will be unique enough to publish it.

 

CytoGene has no role in Publication of data obtained in this project. Independently candidate can publish it.

Candidate may put a name from cytoGene in authorship while publishing the data or can acknowledge us.

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Project Fee - ₹16000

PAYMENT SCHEDULE
AT THE TIME OF REGISTRATION  ₹1,000/-
IN BETWEEN 25 DEC - 31 DEC 2021   ₹5,000/-
IN BETWEEN 25 JAN - 31 JAN 2022  ₹5,000/-
IN BETWEEN 25 FEB - 28 FEB 2022  ₹5,000/-

COMPLETE PAYMENT AT ONE GO    ₹15,000/-

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Important Dates

Date of Notification - 12 Nov 2021
Start Date of Registration - 15 Nov 2021
Last Date of Registration - 05 Dec 2021
Start Date of Project - 01 Jan 2021 (6-8 pm)
Total no of Seat - 30
Selection Criteria - First come first serve
Eligibility -
 Students of UG, PG, PhD Scholar & Faculty Members from any stream of Life Sciences/ Biotechnology

KEY FEATURES OF THE PROJECT

✓   MS Team Online Platform will be used

✓   All the sessions will be recorded

✓   All Candidate will perform their own project

✓   Every topic will slightly vary

✓   Everyone can publish their data

✓   Duration of the project is 3 month

✓   Sessions will be in Evening (06-08 pm)

✓   Total No of Seats – 30 (First Come First Serve)

HOW TO REGISTER

Online Registration: 

Click the blow given button to register online. Fill the form and submit. Open the 

Offline Registration: 

Download MS Word format of Registration form.

Send the duly filled registration form and screenshot of payment by Email to services@cytogene.in or

Whatsapp to 77-0309-2222

Click to download registration form

Mode of Payment: https://www.cytogene.in/mode-of-payment

Last date to Apply: 

05 December 2021

Selection Process: 

First Come First Serve

CONTACT PERSON

Er. Sujeet Kumar Singh

Director

CytoGene Research & Development

Lucknow - 226021

+91-77-0309-2222 , +91-77-0309-3333

services@cytogene.in